ATL 1102
ATL 1102 (Avicursen) is a novel second-generation antisense oligonucleotide to CD49d mRNA
Product Specifications
CAS Number
[350263-41-1]
Product Name Alternative
ISIS-107248; Avicursen
UNSPSC
12352208
Target
Integrin
Type
Oligonucleotides
Related Pathways
Cytoskeleton
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/atl-1102.html
Solubility
10 mM in H2O
Smiles
[ATL1102]
Molecular Formula
C233H327N60O129P19S19
Molecular Weight
7230.14
References & Citations
[1]Duchartre Y, Bachl S, Kim HN, et al. Effects of CD49d-targeted antisense-oligonucleotide on α4 integrin expression and function of acute lymphoblastic leukemia cells: Results of in vitro and in vivo studies. PLoS One. 2017;12 (11) :e0187684. |[2]Limmroth V, Barkhof F, Desem N, Diamond MP, Tachas G; ATL1102 Study Group. CD49d antisense drug ATL1102 reduces disease activity in patients with relapsing-remitting MS [published correction appears in Neurology. 2015 Jan 6;84 (1) :105]. Neurology. 2014;83 (20) :1780-1788.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
Phase 2
Curated Selection
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