Aganirsen
Aganirsen is a 25 mer DNA antisense oligonucleotide, which silences expression of insulin receptor substrate-1 (IRS-1) .
Product Specifications
CAS Number
1146887-67-3
UNSPSC
12352208
Target
Insulin Receptor
Type
Oligonucleotides
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/aganirsen.html
Solubility
10 mM in H2O
Smiles
[Aganirsen]
References & Citations
[1]Cursiefen C, Viaud E, Bock F, et al. Aganirsen antisense oligonucleotide eye drops inhibit keratitis-induced corneal neovascularization and reduce need for transplantation: the I-CAN study. Ophthalmology. 2014;121 (9) :1683-1692.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
Phase 3
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