Hedgehog IN-2
Hedgehog IN-2 (Compound 20) is an inhibitor of Hedgehog pathway with an IC50 value less than 0.003 μM in C3H10T1/2 cells[1].
Product Specifications
CAS Number
[1126365-74-9]
UNSPSC
12352005
Target
Hedgehog
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hedgehog-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(C=C1)OCC2=NC=CC=C2)NC3=C(C)C=CC(C4=NC(C)=CN4)=C3
Molecular Formula
C24H22N4O2
Molecular Weight
398.46
References & Citations
[1]Dakin Leslie, et al. HETEROCYCLIC AMIDES USEFUL FOR THE TREATMENT OF CANCER AND PSORIASIS, USA, US20100311748A [P]. 12/09/2010
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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