Hedgehog IN-2

Hedgehog IN-2 (Compound 20) is an inhibitor of Hedgehog pathway with an IC50 value less than 0.003 μM in C3H10T1/2 cells[1].

Product Specifications

CAS Number

[1126365-74-9]

UNSPSC

12352005

Target

Hedgehog

Type

Reference compound

Related Pathways

Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hedgehog-in-2.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC=C(C=C1)OCC2=NC=CC=C2)NC3=C(C)C=CC(C4=NC(C)=CN4)=C3

Molecular Formula

C24H22N4O2

Molecular Weight

398.46

References & Citations

[1]Dakin Leslie, et al. HETEROCYCLIC AMIDES USEFUL FOR THE TREATMENT OF CANCER AND PSORIASIS, USA, US20100311748A [P]. 12/09/2010

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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