HPK1-IN-36
HPK1-IN-36 (compound 2) is a potent HPK1 inhibitor with an IC50 value of 0.5 nM[1].
Product Specifications
CAS Number
2738518-06-2
UNSPSC
12352005
Target
MAP4K
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hpk1-in-36.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=CC(OC)=CC(CNC)=C2CN1C3=NC(C4=NN=CN4[C@H](CC(F)(F)F)C)=CC=C3.Cl
Molecular Formula
C22H24ClF3N6O2
Molecular Weight
496.91
References & Citations
[1]Omar Ahmad, et al. Isoindolone compounds as hpk1 inhibitors. WO2021224818A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAP4K1/HPK1
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