RIP1 kinase inhibitor 4
RIP1 kinase inhibitor 4 (Example 3) is a BBB-penetrable RIP1 kinase inhibitor (EC50: [1]. RIP1 kinase inhibitor 4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
[2919836-00-1]
UNSPSC
12352005
Target
RIP kinase
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rip1-kinase-inhibitor-4.html
Solubility
10 mM in DMSO
Smiles
NC(N=C1)=NC=C1C#CC2CCC(C2)N3N=C4C(CCC4C5=CC=CC=C5)=C3
Molecular Formula
C23H23N5
Molecular Weight
369.46
References & Citations
[1]Su, Yaning, et al. Preparation of pyrazole and triazole heterocycle derivative as RIP1 kinase inhibitor. Patent. WO2023040870.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
RIPK1
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