TRV-1387
TRV-1387 is a benzofurazan that inhibits the aggregation of tau and amyloid-β[1].
Product Specifications
CAS Number
1569645-63-1
UNSPSC
12352005
Target
Amyloid-β; Tau Protein
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/trv-1387.html
Solubility
10 mM in DMSO
Smiles
FC(F)(C(C1=CC=CC(C2=CC3=NON=C3C(N4CCC(CC4)N5CCCC5)=C2)=C1)O)F
Molecular Formula
C23H25F3N4O2
Molecular Weight
446.47
References & Citations
[1]Rauch JN, et al. Interactions between Microtubule-Associated Protein Tau (MAPT) and Small Molecules. Cold Spring Harb Perspect Med. 2017 Jul 5;7 (7) :a024034.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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