Mcl-1 inhibitor 13
Mcl-1 inhibitor 13 (Example 9) is a MCL-1 inhibitor (Ki: 8.2 nM) . Mcl-1 inhibitor 13 can be used for the research of cancers[1].
Product Specifications
CAS Number
[2445466-06-6]
UNSPSC
12352005
Target
Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mcl-1-inhibitor-13.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=CC=C1C2=NC(COC3=C(C[C@H](C(O)=O)OC4=NC=NN5C4=[C@@]([C@@]6=C(C)C(Cl)=C(OCCN7CCN(C)CC7)C=C6)C(C8=CC=C(F)C=C8)=C5)C=CC=C3)=CC=N2
Molecular Formula
C47H45ClFN7O6
Molecular Weight
858.35
References & Citations
[1]Jincong Zhuo, et al. 2- ((5- (phenyl) -pyrrolo[2,1-f][1,2,4]triazin-4-yl) amino) -3- (phenyl) propanoic acid derivatives and related compounds as mcl-1 enzyme inhibitors for treating cancer. Patent WO2020123994.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Mcl-1
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