ATR-IN-22
ATR-IN-22 (Compound 34) is an orally active ATR inhibitor. ATR-IN-22 inhibits MIAPaCa-2 proliferation (IC50 [1].
Product Specifications
CAS Number
2905312-07-2
UNSPSC
12352005
Target
ATM/ATR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/atr-in-22.html
Solubility
10 mM in DMSO
Smiles
N#CC1(CCC(CC1)N(C)C)C2=CC(N3[C@@H](COCC3)C)=NC4=C2C=CN=C4C5=NNC=C5
Molecular Formula
C25H31N7O
Molecular Weight
445.56
References & Citations
[1]Xie, Yuli, et al. Naphthyridine derivative as ATR inhibitor and method for preparing same. Patent. WO2023016529. 2023-02-16.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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