Fosigotifator

Fosigotifator is modulates the integrated stress response (ISR) for inhibition of ISR-related diseases[1].

Product Specifications

CAS Number

[2415715-84-1]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fosigotifator.html

Solubility

10 mM in DMSO

Smiles

O=C(COC(C=C1)=CC(F)=C1Cl)NC(CCC23NC(COC(C=C4)=CC(F)=C4Cl)=O)(CC2)[C@H](C3)OCO[P](O)(O)=O

Molecular Formula

C25H27Cl2F2N2O9P

Molecular Weight

639.37

Precautions

P261-P280-P302+P352

References & Citations

[1]Martin, et al. Preparation of bicyclooctanyl diamide prodrugs as modulators of the integrated stress pathway useful in treatment of ISR-mediated disorders. World Intellectual Property Organization, WO2020077217 A1. 2020-04-16.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 3

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