Fosigotifator
Fosigotifator is modulates the integrated stress response (ISR) for inhibition of ISR-related diseases[1].
Product Specifications
CAS Number
[2415715-84-1]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fosigotifator.html
Solubility
10 mM in DMSO
Smiles
O=C(COC(C=C1)=CC(F)=C1Cl)NC(CCC23NC(COC(C=C4)=CC(F)=C4Cl)=O)(CC2)[C@H](C3)OCO[P](O)(O)=O
Molecular Formula
C25H27Cl2F2N2O9P
Molecular Weight
639.37
Precautions
P261-P280-P302+P352
References & Citations
[1]Martin, et al. Preparation of bicyclooctanyl diamide prodrugs as modulators of the integrated stress pathway useful in treatment of ISR-mediated disorders. World Intellectual Property Organization, WO2020077217 A1. 2020-04-16.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
Curated Selection
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