Acid Ceramidase-IN-2
Product Specifications
UNSPSC Description
Acid Ceramidase-IN-2 (compound 1) is an acid ceramidase inhibitor with potentially antiproliferative and cytostatic activities. Moreover, human acid ceramidase is overexpressed in prostate cancer cells, indicating potential anti-tumor effect of Acid Ceramidase-IN-2. And Acid Ceramidase-IN-2 hydrolysis can be inhibited by 3 a-ketoamides GT85, GT98 and GT99 inhibits in vitro[1].
Target Antigen
Ceramidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/acid-ceramidase-in-2.html
Purity
99.0
Solubility
10 mM in DMSO
Smiles
CCCCCCCCCCCCCCCC(N[C@@H](CO)[C@H](O)CCOC1=CC=C(C=CC(O2)=O)C2=C1)=O
Molecular Weight
517.70
References & Citations
[1]Bedia C, et al. Synthesis of a novel ceramide analogue and its use in a high-throughput fluorogenic assay for ceramidases. Chembiochem. 2007 Apr 16;8(6):642-8.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-153396/Acid-Ceramidase-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-153396/Acid-Ceramidase-IN-2-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1005497-03-9
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