Aflatoxin Q1
Product Specifications
CAS Number
52819-96-2
UNSPSC Description
Aflatoxin Q1 is a hydroxy metabolite of Aflatoxin B1 (AFB1), which is a mycotoxin produced by Aspergillus flavus (A. flavus). Aflatoxin Q1, as well as and aflatoxin B1 8,9-oxide, is the major oxidative products formed from aflatoxin B1 in human liver microsomes, at all substrate concentrations. the 3 alpha-hydroxylation of aflatoxin B1 to aflatoxin Q1 is a potentially significant detoxication pathway[1][2].
Target Antigen
Fungal
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Solubility
10 mM in DMSO
Smiles
COC1=CC(O[C@]2([H])[C@@]3([H])C=CO2)=C3C(O4)=C1C([C@H](CC5=O)O)=C5C4=O
Molecular Weight
328.27
References & Citations
[1]Raney KD, et al. Oxidation of aflatoxins and sterigmatocystin by human liver microsomes: significance of aflatoxin Q1 as a detoxication product of aflatoxin B1. Chem Res Toxicol. 1992 Mar-Apr;5(2):202-10. |[2]Yamada M, et al. Detoxification of Aflatoxin B1 Contaminated Maize Using Human CYP3A4. J Microbiol Biotechnol. 2020 Aug 28;30(8):1207-1213.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
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