ATR-IN-21
ATR-IN-21 (compound 60) is a potent ATR inhibitor with an IC50 value of [1].
Product Specifications
CAS Number
[2905312-17-4]
UNSPSC
12352005
Target
ATM/ATR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/atr-in-21.html
Solubility
10 mM in DMSO
Smiles
N#CC1(CCC(CC1)N)C2=CC(N3[C@@H](COCC3)C)=NC4=C2C=CN=C4C5=NNC=C5
Molecular Formula
C23H27N7O
Molecular Weight
417.51
References & Citations
[1]YuLi Xie, et al. Naphthyridine derivative as atr inhibitor and method for preparing same. WO2023016529A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ATR
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