4A3-Cit

4A3-Cit is an ionizable lipid used for the generation of lipid nanoparticles (LNPs) .

Product Specifications

CAS Number

[2768211-13-6]

UNSPSC

12352200

Target

Liposome

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/4a3-cit.html

Purity

98.04

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(CCN(CCCN(CCCN(CCC(OCCOC(C(CSCCC(CC/C=C(C)/C)C)C)=O)=O)CCC(OCCOC(C(CSCCC(CC/C=C(C)/C)C)C)=O)=O)C)CCC(OCCOC(C(CSCCC(CC/C=C(C)/C)C)C)=O)=O)OCCOC(C(CSCCC(CC/C=C(C)\C)C)C)=O

Molecular Formula

C83H147N3O16S4

Molecular Weight

1571.33

References & Citations

[1]Lee SM, Cheng Q, Yu X, Liu S, Johnson LT, Siegwart DJ. A Systematic Study of Unsaturation in Lipid Nanoparticles Leads to Improved mRNA Transfection In Vivo. Angew Chem Int Ed Engl. 2021;60 (11) :5848-5853.