TNF-α-IN-9

TNF-α-IN-9 (compound 48) is a analog of NDM-1 inhibitor-3 (HY-150758) . TNF-α-IN-9 is a TNF-α inhibitor. TNF-α-IN-9 shows low inhibitory activity[1].

Product Specifications

CAS Number

[2054199-25-4]

UNSPSC

12352005

Target

TNF Receptor

Type

Reference compound

Related Pathways

Apoptosis

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/tnf-α-in-9.html

Solubility

10 mM in DMSO

Smiles

O=C1C2=C(O)C=CC=C2C/C1=C\C3=CC(O)=C(C=C3)OC

Molecular Formula

C17H14O4

Molecular Weight

282.29

References & Citations

[1]Kadayat TM, et al. Discovery and structure-activity relationship studies of 2-benzylidene-2,3-dihydro-1H-inden-1-one and benzofuran-3 (2H) -one derivatives as a novel class of potential therapeutics for inflammatory bowel disease. Eur J Med Chem. 2017 Sep 8;137:575-597.