(7R) -Elisrasib
KRASG12C IN-2 (compound 17) is an orally active KRASG12C inhibitor. KRASG12C IN-2 inhibits tumor growth in mice[1].
Product Specifications
CAS Number
[2706637-12-7]
Product Name Alternative
(7R) -D3S-001
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/krasg12c-in-2.html
Purity
99.52
Solubility
10 mM in DMSO
Smiles
FC(F)(F)C(C(C)=CC(N)=C1F)=C1[C@H]2CC3=NC(OC[C@@]45N(CCC5)C[C@@H](C4)F)=NC(N6C[C@@H](N(CC6)C(C(F)=C)=O)CC#N)=C3CO2
Molecular Formula
C32H35F6N7O3
Molecular Weight
679.66
References & Citations
[1]Zhang Yang, et al. Pyrimidoheterocyclic compounds and application thereof. WO2021180181A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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