IACS-9439
IACS-9439 is a potent, selective, and orally active CSF1R inhibitor with a Ki value of 1 nM inhibitor. IACS-9439 can be used for advanced solid tumors research[1].
Product Specifications
CAS Number
2231259-36-0
UNSPSC
12352005
Target
C-Fms
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/iacs-9439.html
Solubility
10 mM in DMSO
Smiles
COC1=C2C(SC(N[C@@H]3[C@H](CCCC3)O)=N2)=CC(OCC4=NC(NC5=CN(N=C5)C)=NC=C4)=C1
Molecular Formula
C23H27N7O3S
Molecular Weight
481.57
References & Citations
[1]Barbara Czako, et al. Discovery of IACS-9439, a Potent, Exquisitely Selective, and Orally Bioavailable Inhibitor of CSF1R. J Med Chem. 2020 Sep 10;63 (17) :9888-9911.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
139868 2500 Roll (2500 Label (s) x 1 Roll)
THT-15-729-2.5 Pre-sized Labels for Printers
Sign In for Pricing
View Details