GSK217

GSK217 is a potent, selective, and highly soluble bromo and extraterminal domain (BET) second bromodomain (BD2) inhibitor. GSK217 can be used for the research of oncology and immune inflammation research[1].

Product Specifications

CAS Number

[2748687-92-3]

UNSPSC

12352005

Target

Epigenetic Reader Domain

Type

Reference compound

Related Pathways

Epigenetics

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/gsk217.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC(C2=CN(C)N=N2)=NC(CC3=C4C=CNC4=CC=C3)=C1)NCC

Molecular Formula

C20H20N6O

Molecular Weight

360.41

References & Citations

[1]Aylott HE, et al. Template-Hopping Approach Leads to Potent, Selective, and Highly Soluble Bromo and Extraterminal Domain (BET) Second Bromodomain (BD2) Inhibitors. J Med Chem. 2021 Mar 25;64 (6) :3249-3281.