GSK217
GSK217 is a potent, selective, and highly soluble bromo and extraterminal domain (BET) second bromodomain (BD2) inhibitor. GSK217 can be used for the research of oncology and immune inflammation research[1].
Product Specifications
CAS Number
[2748687-92-3]
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/gsk217.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(C2=CN(C)N=N2)=NC(CC3=C4C=CNC4=CC=C3)=C1)NCC
Molecular Formula
C20H20N6O
Molecular Weight
360.41
References & Citations
[1]Aylott HE, et al. Template-Hopping Approach Leads to Potent, Selective, and Highly Soluble Bromo and Extraterminal Domain (BET) Second Bromodomain (BD2) Inhibitors. J Med Chem. 2021 Mar 25;64 (6) :3249-3281.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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