Py-MAA-Val-Cit-PAB-DX8951
Py-MAA-Val-Cit-PAB-DX8951 is a purine toxin. Py-MAA-Val-Cit-PAB-DX8951 can be used as an intermediate in the synthesis of antibody-drug conjugates[1].
Product Specifications
CAS Number
[2504068-37-3]
UNSPSC
12352203
Target
Nucleoside Antimetabolite/Analog
Type
ADC Related
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/py-maa-val-cit-pab-dx8951.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CN(CN(C1)C(C=C)=O)C(C=C)=O)CCSCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC(C=C2)=CC=C2COC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O
Molecular Formula
C57H66FN11O13S
Molecular Weight
1164.26
References & Citations
[1]Yu Zhaoxing, et al. One-pot preparation method of antibody drug conjugate intermediates: China, CN111620927 A, 2020-09-04.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Curated Selection
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