CD19 car circRNA-LNP
Product Specifications
UNSPSC Description
CD19 car circRNA-LNP is a lipid nanoparticle (LNP) containing CD19 car circRNA, suitable for detection of RNA delivery, translation efficiency, cell viability, etc. CD19 car circRNA can be used in chimeric antigen receptor T cell immunotherapy (CAR-CD19). The CD19 car is a chimeric antigen receptor. Among them, CD19 is a CD molecule expressed by B cells (i.e. leukocyte differentiation antigen), an important membrane antigen involved in B cell proliferation, differentiation, activation and antibody production, and can also promote BCR signal transduction[1][2].
Target Antigen
CD19; Liposome
Type
Biochemical Assay Reagents
Related Pathways
Immunology/Inflammation;Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cd19-car-circrna-lnp.html
Solubility
10 mM in DMSO
Smiles
[CD19 car circRNA-LNP]
References & Citations
[1]Xu Y, et al. Closely related T-memory stem cells correlate with in vivo expansion of CAR.CD19-T cells and are preserved by IL-7 and IL-15. Blood. 2014 Jun 12;123(24):3750-9. |[2]Li X, et al. CD19, from bench to bedside. Immunol Lett. 2017 Mar;183:86-95.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-153234/CD19-car-circRNA-LNP-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-153234/
Clinical Information
No Development Reported
Curated Selection
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