MDM2/XIAP-IN-1
Product Specifications
UNSPSC Description
MDM2/XIAP-IN-1 (compound 14) is an orally active inhibitor of dual MDM2/XIAP. MDM2/XIAP-IN-1 has anti-cancer activity with an IC50 value of 0.3 μM, which can be used in cance rescrch[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mdm2-xiap-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(OC)C1=CC=C(C2NC3=C(C=C(S(=O)(NC4=CC=C(C)C(C)=C4)=O)C=C3)C5C2CC=C5)C=C1
Molecular Weight
488.60
References & Citations
[1]Zhongzhi Wu, et al. Discovery of N-(3,4-Dimethylphenyl)-4-(4-isobutyrylphenyl)-2,3,3a,4,5,9b-hexahydrofuro[3,2-c]quinoline-8-sulfonamide as a Potent Dual MDM2/XIAP Inhibitor. Med. Chem. 2021, 64, 4.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-153199/MDM2-XIAP-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-153199/
Clinical Information
No Development Reported
CAS Number
359595-95-2
Curated Selection
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