GalNAc-L96 (free base)
GalNAc-L96 free base is a triantennary GalNAc ligand that can be used for the synthesis of GalNAc-siRNA[1]. GalNAc is a ligand of ASGPR (asialoglycoprotein receptor) .
Product Specifications
CAS Number
1159408-61-3
UNSPSC
12352005
Hazard Statement
H315-H319
Target
Drug Intermediate
Type
Oligonucleotides
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/galnac-l96-free-base.html
Solubility
10 mM in DMSO
Smiles
CC(N[C@H]([C@H]([C@H]([C@H](O1)COC(C)=O)OC(C)=O)OC(C)=O)[C@@H]1OCCCCC(NCCCNC(CCOCC(COCCC(NCCCNC(CCCCO[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)COC(C)=O)OC(C)=O)OC(C)=O)NC(C)=O)=O)=O)(COCCC(NCCCNC(CCCCO[C@H]3[C@@H]([C@H]([C@H]([C@H](O3)COC(C)=O)OC(C)=O)OC(C)=O)NC(C)=O)=O)=O)NC(CCCCCCCCCCC(N(C[C@@H](C4)OC(CCC(O)=O)=O)[C@@H]4COC(C5=CC=C(C=C5)OC)(C6=CC=CC=C6)C7=CC=C(C=C7)OC)=O)=O)=O)=O)=O
Molecular Formula
C121H179N11O45
Molecular Weight
2507.76
Precautions
P264-P280-P302+P352-P362+P364
References & Citations
[1]Anna Clua, et al. Properties of Parallel Tetramolecular G-Quadruplex Carrying N-Acetylgalactosamine as Potential Enhancer for Oligonucleotide Delivery to Hepatocytes. Molecules. 2022 Jun 20;27 (12) :3944.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
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