PAT-IN-2
PAT-IN-2 is a protein acyl transferases (PAT) inhibitor. PAT-IN-2 competitively inhibits Erf2 autopalmitoylation (WO2017011518A1; compound 25) [1].
Product Specifications
CAS Number
2066572-01-6
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pat-in-2.html
Solubility
10 mM in DMSO
Smiles
CC(C1=CC=C(C=C1)CC(C)C)CN(CCN(C2)CCCC[C@@H]3N(CCNC3)CCC4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)[C@H]2CC5=CC=C(C=C5)O
Molecular Formula
C42H56F6N4O
Molecular Weight
746.91
References & Citations
[1]Robert Joseph DESCHENES, et al. Protein acyl transferase inhibitors and methods of treatment. WO2017011518A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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