Bemoradan
Bemoradan (compound 10a) is an orally active and selective canine Phosphodiesterase (PDE) fraction III inhibitor. Bemoradan is a long-acting, potent, inotropic vasodilator and a novel cardiotonic agent, and can be used in congestive heart failure research[1].
Product Specifications
CAS Number
112018-01-6
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/bemoradan.html
Solubility
10 mM in DMSO
Smiles
O=C1NN=C(C(C1)C)C2=CC3=C(NC(CO3)=O)C=C2
Molecular Formula
C13H13N3O3
Molecular Weight
259.26
References & Citations
[1]Combs DW, et al. 6-Benzoxazinylpyridazin-3-ones: potent, long-acting positive inotrope and peripheral vasodilator agents. J Med Chem. 1990 Jan;33 (1) :380-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
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