PI3K/mTOR Inhibitor-13

PI3K/mTOR Inhibitor-13 is an orally active dual inhibitor of phosphoinositol 3-kinase (PI3K) and mTOR kinase. PI3K/mTOR Inhibitor-13 has potential applications in sexual diseases, solid tumor and idiopathic pulmonary fibrosis (IPF) [1][2].

Product Specifications

CAS Number

[1621718-37-3]

UNSPSC

12352005

Target

MTOR; PI3K

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pi3k-mtor-inhibitor-13.html

Solubility

10 mM in DMSO

Smiles

N#CC1=C2C=C(C3=CC(NS(=O)(C4=CC=C(C=C4F)F)=O)=C(OC)N=C3)C=CN2N=C1

Molecular Formula

C20H13F2N5O3S

Molecular Weight

441.41

References & Citations

[1]Cao S, et al. Pharmaceutical combination or pharmaceutical composition for treatment of fibrotic diseases. World Intellectual Property Organization. WO2020078445.|[2]Xi N, et al. Aromatic heterocyclic compounds, pharmaceutical composition containing compounds and application of pharmaceutical composition.China.CN103965199.