Rongliflozin
Rongliflozin (DJT1116PG) is a selective and orally active inhibitor of sodium-glucose co-transporter-2 (SGLT-2) . Rongliflozin can be used for the research of type 2 diabetes mellitus (T2DM) [1].
Product Specifications
CAS Number
2648020-91-9
Product Name Alternative
DJT1116PG
UNSPSC
12352211
Target
SGLT
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/rongliflozin.html
Solubility
10 mM in DMSO
Smiles
OC([C@H]1NC(CC1)=O)=O.O[C@H]2[C@]3(C4=CC(CC5=CC=C(C=C5)OCC)=C(C=C4)Cl)O[C@@](CO3)([C@H]([C@@H]2O)O)[C@H](O)C.O.[1.25]
Molecular Formula
C23H27ClO7.C5H7NO3.5/4H2O
Molecular Weight
602.55
References & Citations
[1]Zhang H, et al. Pharmacokinetics and pharmacodynamics of rongliflozin, a novel selective inhibitor of sodium-glucose co-transporter-2, in people with type 2 diabetes mellitus. Diabetes Obes Metab. 2020 Feb;22 (2) :191-202.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
SGLT2
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