Rongliflozin

Rongliflozin (DJT1116PG) is a selective and orally active inhibitor of sodium-glucose co-transporter-2 (SGLT-2) . Rongliflozin can be used for the research of type 2 diabetes mellitus (T2DM) [1].

Product Specifications

CAS Number

[2648020-91-9]

Product Name Alternative

DJT1116PG

UNSPSC

12352211

Target

SGLT

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/rongliflozin.html

Solubility

10 mM in DMSO

Smiles

OC([C@H]1NC(CC1)=O)=O.O[C@H]2[C@]3(C4=CC(CC5=CC=C(C=C5)OCC)=C(C=C4)Cl)O[C@@](CO3)([C@H]([C@@H]2O)O)[C@H](O)C.O.[1.25]

Molecular Formula

C23H27ClO7.C5H7NO3.5/4H2O

Molecular Weight

602.55

References & Citations

[1]Zhang H, et al. Pharmacokinetics and pharmacodynamics of rongliflozin, a novel selective inhibitor of sodium-glucose co-transporter-2, in people with type 2 diabetes mellitus. Diabetes Obes Metab. 2020 Feb;22 (2) :191-202.