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3'-O-Me-m7G (5') ppp (5') A solution (100mM)

3'-O-Me-m7G (5') ppp (5') A (ARCA cap) solution (100mM), anti-reverse cap analog, has a special RNA cap structure. Is a common feature of the mRNA of some RNA viruses and eukaryotes. RNA cap structures serve as signals for translation initiation[1].

Product Specifications

Product Name Alternative

ARCA cap solution (100mM)

UNSPSC

12352200

Target

DNA/RNA Synthesis

Type

Biochemical Assay Reagents

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/3-o-me-m7g-5-ppp-5-a.html

Concentration

100 mM * 100 μL in Water

Purity

99.64

Solubility

10 mM in DMSO

Smiles

O[C@@H]1[C@H](OC)[C@@H](COP(OP(OP(OC[C@@H]2[C@@H](O)[C@@H](O)[C@H](N3C(N=CN=C4N)=C4N=C3)O2)([O-])=O)([O-])=O)([O-])=O)O[C@H]1N5C(N=C(N)NC6=O)=C6[N+](C)=C5.[NH4+].[NH4+]

Molecular Formula

C22H37N12O17P3

Molecular Weight

834.52

References & Citations

[1]Hadas Y, et al. Optimizing Modified mRNA In Vitro Synthesis Protocol for Heart Gene Therapy. Mol Ther Methods Clin Dev. 2019 Jul 30;14:300-305.

Shipping Conditions

Dry Ice

Storage Conditions

Solution, -20°C, 1 year

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Curated Selection

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