OICR12694
OICR12694 (JNJ-65234637) is an orally active inhibitor of B cell lymphoma 6 (BCL6) [1].
Product Specifications
CAS Number
2360625-97-2
Product Name Alternative
JNJ-65234637
UNSPSC
12352005
Target
Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/oicr12694.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(N=C3N1CCC3)N(CC(NC4=C(Cl)C(F)=NC(N5[C@H](CN(CC5)C)C)=C4)=O)C=C2C6=CC(C(N)=O)=C(C(F)=C6F)O
Molecular Formula
C29H28ClF3N8O4
Molecular Weight
645.03
References & Citations
[1]Mamai A, et al. Discovery of OICR12694: A Novel, Potent, Selective, and Orally Bioavailable BCL6 BTB Inhibitor. ACS Med Chem Lett. 2023 Jan 12;14 (2) :199-210.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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