CDK4/6-IN-16
CDK4/6-IN-16 (example 195) is a potent CDK4 and CDK6 inhibitor, with an IC50 of 0.013 μM for CDK4. CDK4/6-IN-16 can be used for the research of CDK4-mediated disorders, such as cancer[1].
Product Specifications
CAS Number
1169694-98-7
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdk4-6-in-16.html
Solubility
10 mM in DMSO
Smiles
FC1=NC=CC2=C1N(C3CCCC3)C4=C2C=NC(NC5=NC=C(N6CCC(CC6)N(CCO)C)C=C5)=N4
Molecular Formula
C27H33FN8O
Molecular Weight
504.60
References & Citations
[1]Richard V. Connors, et al. Fused pyridine, pyrimidine and triazine compounds as cell cycle inhibitors. WO2009085185A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK4; CDK6
Available Sizes
Frequently Asked Questions
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