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CDK4/6-IN-16

CDK4/6-IN-16 (example 195) is a potent CDK4 and CDK6 inhibitor, with an IC50 of 0.013 μM for CDK4. CDK4/6-IN-16 can be used for the research of CDK4-mediated disorders, such as cancer[1].

Product Specifications

CAS Number

1169694-98-7

UNSPSC

12352005

Target

CDK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cdk4-6-in-16.html

Solubility

10 mM in DMSO

Smiles

FC1=NC=CC2=C1N(C3CCCC3)C4=C2C=NC(NC5=NC=C(N6CCC(CC6)N(CCO)C)C=C5)=N4

Molecular Formula

C27H33FN8O

Molecular Weight

504.60

References & Citations

[1]Richard V. Connors, et al. Fused pyridine, pyrimidine and triazine compounds as cell cycle inhibitors. WO2009085185A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CDK4; CDK6

Available Sizes

Frequently Asked Questions

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