TLR7 agonist 8
TLR7 agonist 8 (compound IIb-34) is an TLR7 agonist with an EC50 value of ~4 nM[1].
Product Specifications
CAS Number
2380231-81-0
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tlr7-agonist-8.html
Solubility
10 mM in DMSO
Smiles
OC(N1C2=NC(OCC/C=C\CC3=CC(C1)=CC=C3C4=CC=C(C=C4)CNC5CCOCC5)=N6)=NC2=C6N
Molecular Formula
C29H32N6O3
Molecular Weight
512.60
References & Citations
[1]Purandare AV, et al. Preparation of macrocyclic purine compounds as toll-like receptor 7 (TLR7) agonists: World Intellectual Property Organization, WO2019209811 A1. 2019-10-31.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TLR7
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