TLR7 agonist 8

TLR7 agonist 8 (compound IIb-34) is an TLR7 agonist with an EC50 value of ~4 nM[1].

Product Specifications

CAS Number

2380231-81-0

UNSPSC

12352005

Target

Toll-like Receptor (TLR)

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/tlr7-agonist-8.html

Solubility

10 mM in DMSO

Smiles

OC(N1C2=NC(OCC/C=C\CC3=CC(C1)=CC=C3C4=CC=C(C=C4)CNC5CCOCC5)=N6)=NC2=C6N

Molecular Formula

C29H32N6O3

Molecular Weight

512.60

References & Citations

[1]Purandare AV, et al. Preparation of macrocyclic purine compounds as toll-like receptor 7 (TLR7) agonists: World Intellectual Property Organization, WO2019209811 A1. 2019-10-31.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

TLR7

More Discoveries

Explore Other Products

Browse additional items from our catalog

11937086 1.0 µg

Ankrd17 3'UTR Lenti-reporter-Luc Vector

View Details

NBP2-70422B 0.1 mL

Mouse Monoclonal COL15A1 Antibody (OTI1C5) [Biotin]

View Details

MBS1496326-01 0.05 mg

MED28 Antibody, FITC conjugated

View Details

MBS1496326-02 0.1 mg

MED28 Antibody, FITC conjugated

View Details

MBS1496326-03 5x 0.1 mg

MED28 Antibody, FITC conjugated

View Details

K6675201 3x 1.0 µg

Creg1 sgRNA CRISPR Lentivector set (Rat)

View Details