Axl/Mer/CSF1R-IN-1
Axl/Mer-IN-1 (Compound 1) is an Axl/Mer receptor tyrosine kinase (Axl/Mer RTK) and CSF1R inhibitor with Kds of [1].
Product Specifications
CAS Number
[2394874-60-1]
UNSPSC
12352005
Target
C-Fms; TAM Receptor
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/axl-mer-csf1r-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NN(CC)C(C)=C1OCC(F)(F)F)NC2=NC=C(C=C2)OC3=C4C=C(OC)C(OC)=CC4=NC=C3
Molecular Formula
C25H24F3N5O5
Molecular Weight
531.48
References & Citations
[1]Kiyean NAM, et al. Quinoline derivatives as inhibitors of axl/mer rtk and csf1r. Patent WO2019229251A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Axl; Mer
Curated Selection
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