N2-iso-Butyroyl-7'-O-DMT-morpholinoguanine
N2-iso-Butyroyl-7'-O-DMT-morpholinoguanine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) [1].
Product Specifications
CAS Number
2243974-78-7
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/n2-iso-butyroyl-7-o-dmt-morpholinoguanine.html
Solubility
10 mM in DMSO
Smiles
O=C(N=C(N1)NC(C(C)C)=O)C(N=C2)=C1N2[C@@H](CNC3)O[C@@H]3COC(C4=CC=C(C=C4)OC)(C5=CC=CC=C5)C6=CC=C(C=C6)OC
Molecular Formula
C35H38N6O6
Molecular Weight
638.71
References & Citations
[1]Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100 (11) :6646-51.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC040218-100 1x 100 µL
CD100 (Semaphorin-4D) (A8), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC550633-500 1x 500 µL
Von Willebrand Factor (3E2D10), CF555 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC740633-100 1x 100 µL
Von Willebrand Factor (3E2D10), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC471620-100 1x 100 µL
CD10 (Membrane Metalloendopeptidase) (MME/1620), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC681170-100 1x 100 µL
Vimentin (VM1170), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details