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2'-Deoxy-5'-O-DMT-N6-Fmoc-adenosine 3'CE-phosphoramidite

2'-Deoxy-5'-O-DMT-N6-Fmoc-adenosine 3'CE-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) [1].

Product Specifications

CAS Number

[109420-86-2]

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

DNA/RNA Synthesis

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/2-deoxy-5-o-dmt-n6-fmoc-adenosine-3-ce-phosphoramidite.html

Solubility

10 mM in DMSO

Smiles

COC(C=C1)=CC=C1C(C2=CC=C(OC)C=C2)(C3=CC=CC=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)C[C@H](N(C=N5)C6=C5C(NC(OCC7C8=C(C=CC=C8)C9=C7C=CC=C9)=O)=NC=N6)O4

Molecular Formula

C55H58N7O8P

Molecular Weight

976.06

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26 (6) :1490-1500.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Available Sizes

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