4-Chloro-7- (2-deoxy-3,5-bis-O- (p-toluoyl) -β-D-ribofuranosyl) -7H-pyrrolo[2,3-d]pyrimidine
4-Chloro-7- (2-deoxy-3,5-bis-O- (p-toluoyl) -β-D-ribofuranosyl) -7H-pyrrolo[2,3-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects[1].
Product Specifications
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/4-chloro-7-2-deoxy-3-5-bis-o-p-toluoyl-β-d-ribofuranosyl-7h-pyrrolo-2-3-d-pyrimidine.html
Solubility
10 mM in DMSO
Smiles
ClC1=NC=NC2=C1C=CN2[C@@H]3O[C@H](COC(C4=CC=C(C)C=C4)=O)[C@@H](OC(C5=CC=C(C)C=C5)=O)C3
Molecular Formula
C27H24ClN3O5
Molecular Weight
505.95
References & Citations
[1]Galmarini CM, et al. Pyrimidine nucleoside analogs in cancer treatment. Expert Rev Anticancer Ther. 2003 Oct;3 (5) :717-28.
Shipping Conditions
Room temperature
Product Datasheet
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-152977/
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
CAS Number
[91713-43-8]
Available Sizes
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