STING agonist-27

STING agonist-27 (CF509) is a non-nucleotide small-molecule STING agonist. STING agonist-23 activates STING, exhibits activity against SARS-CoV series strains[1].

Product Specifications

CAS Number

[2868261-45-2]

UNSPSC

12352005

Target

STING

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/sting-agonist-27.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC(N=C(N2CCCCN3C(NC(C4=CC(C)=NN4CC)=O)=NC5=C3C(OCCCN6CCOCC6)=CC(C(N)=O)=C5)NC(C7=CC(C)=NN7CC)=O)=C2N=C1)N

Molecular Formula

C40H50N14O6

Molecular Weight

822.92

References & Citations

[1]Liu Z, et al. A novel STING agonist-adjuvanted pan-sarbecovirus vaccine elicits potent and durable neutralizing antibody and T cell responses in mice, rabbits and NHPs. Cell Res. 2022 Mar;32 (3) :269-287.