(Rac) -MTK458

(Rac) -MTK458 (compound 16) is an activator of mitophagy. EP-0035985 is the isomer of EP-0035985[1].

Product Specifications

CAS Number

[2499962-44-4]

Product Name Alternative

(Rac) -EP-0035985

UNSPSC

12352005

Target

Mitophagy

Type

Reference compound

Related Pathways

Autophagy

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/rac-mtk458.html

Solubility

10 mM in DMSO

Smiles

FC(F)(C1=CC2=C(NC3C4=C(CCC3)C=CC=C4)N=CN=C2N1)F

Molecular Formula

C17H15F3N4

Molecular Weight

332.32

References & Citations

[1]De Roulet D, et al. Preparation of purinamines and pyrrolopyrimidinamines, compositions and methods of using the same for treatment of neurodegenerative and mitochondrial disease. World Intellectual Property Organization, WO2020206363 A1 2020-10-08.