(Rac)-MTK458
Product Specifications
UNSPSC Description
(Rac)-MTK458 (compound 16) is an activator of mitophagy. EP-0035985 is the isomer of EP-0035985[1].
Target Antigen
Mitophagy
Type
Reference compound
Related Pathways
Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rac-mtk458.html
Solubility
10 mM in DMSO
Smiles
FC(F)(C1=CC2=C(NC3C4=C(CCC3)C=CC=C4)N=CN=C2N1)F
Molecular Weight
332.32
References & Citations
[1]De Roulet D, et al. Preparation of purinamines and pyrrolopyrimidinamines, compositions and methods of using the same for treatment of neurodegenerative and mitochondrial disease. World Intellectual Property Organization, WO2020206363 A1 2020-10-08.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-152943A/Rac-MTK458-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-152943A/
Clinical Information
No Development Reported
CAS Number
2499962-44-4
Curated Selection
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