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JTV-519

JTV-519 (K201) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. Antiarrhythmic and cardioprotective properties[1][2].

Product Specifications

CAS Number

1038410-88-6

Product Name Alternative

K201

UNSPSC

12352005

Target

Calcium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/jtv-519.html

Solubility

10 mM in DMSO

Smiles

COC1=CC=C2C(CN(C(CCN3CCC(CC4=CC=CC=C4)CC3)=O)CCS2)=C1.Cl

Molecular Formula

C25H33ClN2O2S

Molecular Weight

461.06

References & Citations

2+2+

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 2

Frequently Asked Questions

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