Isocytidine
2-Amino-1-β-D-ribofuranosyl-4 (1H) -pyrimidinone is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[489-59-8]
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/isocytidine.html
Solubility
10 mM in DMSO
Smiles
O=C1N=C(N)N([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C=C1
Molecular Formula
C9H13N3O5
Molecular Weight
243.22
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-152877/Isocytidine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-152877/
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
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