Dazostinag

Dazostinag (TAK-676 free base) is an agonist of stimulator of interferon genes (STING) protein with antineoplastic activity. Dazostinag can serve as a playload to synthesis antibody-drug conjugates (ADCs) [1][2].

Product Specifications

CAS Number

[2553413-86-6]

Product Name Alternative

TAK-676 (free base)

UNSPSC

12352005

Target

STING

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dazostinag.html

Solubility

10 mM in DMSO

Smiles

FC1=CN([C@H]2[C@H](O[P@@](OC[C@@H]3[C@@H](O4)[C@@H](F)[C@H](N5C6=NC=NC(N)=C6N=C5)O3)(S)=O)[C@H](O)[C@@H](COP4(S)=O)O2)C7=C1C(N=CN7)=O

Molecular Formula

C21H22F2N8O10P2S2

Molecular Weight

710.52

References & Citations

[1]Ishii Yumiko, et al. Antibody drug conjugates comprising STING modulators: World Intellectual Property Organization, WO2020229982. 2020-11-19.|[2]WHO Drug Information-World Health Organization (WHO) .