3-Methyl-5-β-D-ribofuranosyl-2,4 (1H,3H) -pyrimidinedione
3-Methyl-5-β-D-ribofuranosyl-2,4 (1H,3H) -pyrimidinedione is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[81691-06-7]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/3-methyl-5-β-d-ribofuranosyl-2-4-1h-3h-pyrimidinedione.html
Solubility
10 mM in DMSO
Smiles
O=C(NC=C1[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)N(C)C1=O
Molecular Formula
C10H14N2O6
Molecular Weight
258.23
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
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