9- (2’-Deoxy-2’-fluoro-β-D-arabinofuranosyl) -9H-purine
9- (2’-Deoxy-2’-fluoro-β-D-arabinofuranosyl) -9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
109304-16-7
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/9-2-deoxy-2-fluoro-β-d-arabinofuranosyl-9h-purine.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@H](F)[C@H](N(C=N2)C3=C2C=NC=N3)O[C@@H]1CO
Molecular Formula
C10H11FN4O3
Molecular Weight
254.22
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Frequently Asked Questions
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