2-Chloro-3’-deoxy-3’-fluoroadenosine
2-Chloro-3’-deoxy-3’-fluoroadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/2-chloro-3-deoxy-3-fluoroadenosine.html
Solubility
10 mM in DMSO
Smiles
NC1=C2C(N([C@@H]3O[C@H](CO)[C@@H](F)[C@H]3O)C=N2)=NC(Cl)=N1
Molecular Formula
C10H11ClFN5O3
Molecular Weight
303.68
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-152778/2-Chloro-3-deoxy-3-fluoroadenosine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-152778/
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
CAS Number
[122654-30-2]
Available Sizes
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