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3′-Deoxy-3′-fluorocytidine

3′-Deoxy-3′-fluorocytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Product Specifications

CAS Number

123402-20-0

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/3-deoxy-3-fluorocytidine.html

Solubility

10 mM in DMSO

Smiles

NC(C=CN1[C@H]2[C@H](O)[C@H](F)[C@@H](CO)O2)=NC1=O

Molecular Formula

C9H12FN3O4

Molecular Weight

245.21

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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