6- (2-O-Methyl-beta-D-ribofuranosyl) -3- (2-oxo-propyl) -6H-imidazo[1,2-c]pyrimidin-5-one
Selected Variant
HY-152770
Size: 1 Each
6- ((2R,3R,4R,5R) -4-Hydroxy-5- (hydroxymethyl) -3-methoxytetrahydrofuran-2-yl) -3- (2-oxopropyl) imidazo[1,2-c]pyrimidin-5 (6H) -one is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
2095417-54-0
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/6-2-o-methyl-beta-d-ribofuranosyl-3-2-oxo-propyl-6h-imidazo-1-2-c-pyrimidin-5-one.html
Solubility
10 mM in DMSO
Smiles
O=C1N2C(C=CN1[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3OC)=NC=C2CC(C)=O
Molecular Formula
C15H19N3O6
Molecular Weight
337.33
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Price
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