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Urease-IN-4

Urease-IN-4 is an effective inhibitor of urease with an IC50 value of 1.64 µM. Urease-IN-4 has low cytotoxicity and shows inhibitory activity on P. vulgaris with an IC50 value of 15.27 µg/mL[1].

Product Specifications

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/urease-in-4.html

Solubility

10 mM in DMSO

Smiles

CCCCNC(CC1SC(N(C1=O)CC2=CC=CC=C2)=O)=O

Molecular Formula

C16H20N2O3S

Molecular Weight

320.41

References & Citations

[1]Dastyafteh N, et al. New thioxothiazolidinyl-acetamides derivatives as potent urease inhibitors: design, synthesis, in vitro inhibition, and molecular dynamic simulation. Sci Rep. 2023 Jan 2;13 (1) :21.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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