2-Hydroxy-2’-deoxy-2’-fluoro-beta-D-arabino adenosine
2-Hydroxy-2’-de oxy-2’-fluoro-beta-D-arabino adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[899827-82-8]
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/2-hydroxy-2-deoxy-2-fluoro-beta-d-arabino-adenosine.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@H](F)[C@H](N(C=N2)C3=C2C(N)=NC(N3)=O)O[C@@H]1CO
Molecular Formula
C10H12FN5O4
Molecular Weight
285.23
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
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