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2-Hydroxy-2’-deoxy-2’-fluoro-beta-D-arabino adenosine

2-Hydroxy-2’-de oxy-2’-fluoro-beta-D-arabino adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Product Specifications

CAS Number

[899827-82-8]

UNSPSC

12352005

Target

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/2-hydroxy-2-deoxy-2-fluoro-beta-d-arabino-adenosine.html

Solubility

10 mM in DMSO

Smiles

O[C@H]1[C@H](F)[C@H](N(C=N2)C3=C2C(N)=NC(N3)=O)O[C@@H]1CO

Molecular Formula

C10H12FN5O4

Molecular Weight

285.23

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Curated Selection

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